The INIA-Stress consortium characterizes stress and alcohol effects on the
nervous system at all levels, and in organisms ranging from mice to monkeys
and humans. We employ a wide range of technologies including genetic analysis
and measurements of ion channel function, synaptic activity and activity of
neurons within active circuits in vivo, as well as analysis of stress-related
behaviors and alcohol intake. The INIA has increased our understanding of the
molecular, cellular and systems-based neuroadaptive changes that take place
in the brain as a consequence of alcohol/stress interactions.
A main goal of the informatics component of the INIA consortium is to promote
INIA collaboration and provide INIA information management through development
of collaborative bioinformatics. A secondary goal is to promote integrative
and comparative bioinformatics by developing tools for computational analysis,
data mining, interoperability and data integration.